Chapter 8: What can be done? Treatments for urinary incontinence and pelvic floor prolapse:

Surgical procedures to treat overactive bladder

Surgery is indicated only when other means to treat your overactive bladder symptoms have failed to do so. The great majority of women will be adequately treated with behavioral modification, physiotherapy and medication. Once you have given these less invasive treatment modalities a chance and they have not improved your condition,  it is time to consider surgery. Just as in the case of stress urinary incontinence, the spectrum of surgery performed to treat overactive bladder is wide and we will focus on just two types of surgery: bladder augmentation and sacral neuromodulation.

Bladder augmentation

Although considered invasive surgery, this is the most successful operation to treat overactive bladder symptoms. The idea behind it is simple. The bladder is augmented or enlarged with a patch made of your own intestine. A segment of your intestine is isolated from the rest of the intestine. The segment is, like the rest of the intestine, a tubular structure. To convert it to a plate-like structure, the intestine is opened and then configured to a plate form. The bladder is then opened and the plate is sewed to its edges like a patch. This surgery provides a larger bladder that will accommodate larger volume of urine and allow longer lapses of time between each time you urinate, decrease the sensation of urge and may prevent urinary incontinence.

Success rates are high with cure rates up to 90%. Bladder augmentation increases bladder capacity and the ability of the bladder to hold larger volumes of urine, and decreases the number of unwanted bladder contractions.

This surgery is performed under general anesthesia and takes 2-4 hours to complete. You may expect to stay in the hospital for a few days and to carry a catheter to drain the bladder for a period of 3 weeks. Except for the usual complications of surgery discussed before, there are several complications specific to this type of procedure that include reduced ability to void requiring you to empty your bladder by periodically inserting a catheter to your bladder and possible imbalance in the salt concentration in your body. The patch of bowel will still behave as a bowel segment and will secrete some mucous into your urine and will make your urine look cloudy.

Sacral Neuromodulation

This is a relatively new way to treat overactive bladder symptoms. As you recall from the chapter on how your bladder works, normal bladder function is regulated by the nervous system. Nerve fibers from the bladder and from the brain meet at the sacral region (at your lower back) to form a relay station where signals are translated to the final commands given to the bladder. Sacral neuromodulation is a surgical procedure in which an electrode is implanted next to the nerve that leads to the bladder. The electrode is connected to a generator that produces tiny electrical signals. These signals are conveyed to the nerve and from there to the bladder. The exact mechanism is unknown but somehow electrical currents can modulate the bladder and decrease the number of urgency-frequency and urge incontinence episodes.

This treatment is given in two separate stages. First, your response to the electrode is tested with a temporary electrode put at the sacral nerve. This is a minor procedure performed under local anesthesia in an outpatient setting. Once the electrode is in place its correct position is verified by sending a few signals and looking for the response. Since the nerve that simulates the bladder is also the one that simulates certain muscles in your leg, a movement of your toe and a pulling sensation in your rectum radiating to the genitalia will signal that the electrode is in the right position.

You will have this temporary electrode for 3 days. You will have to fill a voiding diary documenting the amount of fluid you take in, the number of times you urinate, and the number of accidents (incontinence episodes) you had. If there is a 50% decrease in your symptoms then you will continue to the next stage which is to implant a permanent electrode.

As opposed to the temporary electrode, the implantation of the permanent electrode is “real” surgery. It is performed while under general anesthesia. A permanent electrode is implanted next to the sacral nerve through an incision in your lower back. A stimulator used to generate electrical pulses is implanted on your flank through a separate incision and connected to the electrode at the sacral nerve. All components are implanted inside your body so that nothing is hanging out. The electrical pulse can be up- or down- regulated and even turned off using a remote control unit that you will receive when you leave the hospital.

The results of the procedure vary from one medical center to another. The first stage where response to the temporary implant is tested, is successful in 20-48% of the cases. As previously mentioned only those women who respond to the first stage will have the second permanent implant. In some medical centers the match between the success of the first stage and the second stage is almost perfect with almost all patients having significant improvement or cure in response to the permanent implantation. Other centers report 20-51% of failure in the second stage.

Complications of surgery include pain and discomfort, migration of the electrode, wound infection and malfunction or failure of the implanted device. Some complications require additional operation.

Surgical procedures for the treatment of pelvic organ prolapse

Many women suffering from urinary incontinence have also some degree of pelvic organ prolapse (POP). POP is the herniation or bulging of the bladder, rectum or uterus through the vaginal walls. Some women refer to this as dropping of the bladder or the vagina and in some extreme cases the prolapsed organ can be seen hanging out of the vagina.

POP is the result of a failure of the supporting ligaments and connective tissues to support the pelvic organs. It is usually the result of trauma to the supporting structures during delivery.

Except for bulging or a sensation of a mass in your vagina, you may experience difficulty emptying your bladder and rectum, pelvic pressure, discomfort, and pain.

If you suffer from any of the above complaints you may want your POP to be repaired. POP can be repaired as a single procedure or in combination with a procedure to treat stress urinary incontinence.

Prolapse of the bladder and the rectum are corrected by overlapping of tissues on both sides of the herniation over the defect in the midline. By this the defect is concealed under the new tissues and reduced to its original position. Severe prolapse of the uterus requires hysterectomy and re-suspension of the vaginal dome or apex to its original position.

Women who have had hysterectomy are at increased risk for prolapse of the vaginal apex or dome. The dome of the vagina can also be re-suspended by tying it to a ligament located deeper in the pelvis (called sacrospinous ligament suspension) or to a bony structure (sacrum). Procedures to correct prolapse of the vaginal dome can be performed either through the vagina or through the abdomen.